tert-butylmagnesium chloride
tert-butylmagnesium chloride
CAS: 677-22-5
Molecular Formula: C4H9ClMg
tert-butylmagnesium chloride - Names and Identifiers
| Name | tert-butylmagnesium chloride |
| Synonyms | tert-butylmagnesium chloride tert-butylmagnesium(1+) chloride |
| CAS | 677-22-5 |
| EINECS | 211-638-6 |
| InChI | InChI=1/C4H9.ClH.Mg/c1-4(2)3;;/h1-3H3;1H;/q;;+1/p-1/rC4H9Mg.ClH/c1-4(2,3)5;/h1-3H3;1H/q+1;/p-1 |
| InChIKey | ZDRJSYVHDMFHSC-UHFFFAOYSA-M |
tert-butylmagnesium chloride - Physico-chemical Properties
| Molecular Formula | C4H9ClMg |
| Molar Mass | 116.872 |
| Density | 0.931 g/mL at 25 °C |
| Melting Point | -108℃ (Tetrahydrofuran) |
| Flash Point | 34 °F |
| Water Solubility | Miscible with alcohol and water. |
| Appearance | Clear brown to dark brown Liquid |
| Storage Condition | 2-8°C |
| Stability | Air & Moisture Sensitive |
| Use | Tert-butyl magnesium chloride is a format reagent, which can be used as a synthetic intermediate in pharmaceutical and chemical industry. Tert-butyl magnesium chloride can be used as a pharmaceutical chemical synthesis intermediates, mainly used in laboratory research and development and chemical pharmaceutical research and development process. |
tert-butylmagnesium chloride - Risk and Safety
| Risk Codes | R12 - Extremely Flammable R14/15 - R19 - May form explosive peroxides R22 - Harmful if swallowed R34 - Causes burns R66 - Repeated exposure may cause skin dryness or cracking R67 - Vapors may cause drowsiness and dizziness R15 - Contact with water liberates extremely flammable gases R11 - Highly Flammable R14 - Reacts violently with water R37 - Irritating to the respiratory system R17 - Spontaneously flammable in air R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S9 - Keep container in a well-ventilated place. S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S29 - Do not empty into drains. S33 - Take precautionary measures against static discharges. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.) S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3399 4.3/PG 1 |
| WGK Germany | 1 |
| FLUKA BRAND F CODES | 1-3-10 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
| Packing Group | I |
tert-butylmagnesium chloride - Upstream Downstream Industry
tert-butylmagnesium chloride - Introduction
melting point -108 ℃ (Tetrahydrofuran)
Density 0.931g/mL at 25 c
Flash point 34 °F
Storage conditions 2-8°C
Morphological Liquid
Color Clear brown to dark brown
Water solubility Miscible with alcohol and water.
Sensitivity Air & Moisture Sensitive
BRN 3535403
InChIKey ZDRJSYVHDMFHSC-UHFFFAOYSA-M
Preparation
Preparation of tert-butyl magnesium chloride: Use sandpaper to remove the oxide film on the surface of the magnesium strip and cut it into fine chips. Weighted 3.6g(0.15 mol) of magnesium chips, added to a four-neck flask equipped with a nitrogen protection device, a stirrer, a reflux condenser and a constant pressure drip funnel (CaCl2 drying tube is installed on the top of the reflux condenser tube), introduced nitrogen into the reaction bottle for about 10 min, removed the air in the four-neck flask, then adjusted the nitrogen flow rate, and continuously introduced extremely small nitrogen into the reaction system. 35 mL of refined tetrahydrofuran is added to the four-neck flask, then 13.9g(0.15 mol) of tert-butyl chloride is weighed, about 3.5g of tert-butyl chloride is added to the four-neck flask first, and the remaining 10.4g of tert-butyl chloride is mixed with 150 mL of refined tetrahydrofuran and then added to a constant pressure separatory funnel. Add a small grain of iodine, slightly hot, a small amount of bubbles are generated, the color of iodine recedes, it is advisable to keep the reaction system slightly boiling after the reaction is initiated, after dropping, stir for 3~4 h, until the magnesium chips disappear completely, showing a gray solution.
safety information
Dangerous goods mark f, c, f
Hazard category code 12-14/15-19-22-34-66-67-15-11-14-37-17-40
Safety instructions 9-16-26-29-33-36/37/39-43-45
Dangerous goods transportation number UN 3399 4.3/PG 1
WGK Germany 1
F 1-3-10
HazardClass 4.3
PackingGroup I
Customs code 29319090
Last Update：2024-04-10 22:29:15
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CAS: 677-22-5
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Product Name: TERT-BUTYLMAGNESIUM CHLORIDE Request for quotationCAS: 677-22-5
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Raw Materials for tert-butylmagnesium chloride
Downstream Products for tert-butylmagnesium chloride